Vimentin Polyclonal Antibody

Catalogue Number: E-AB-70081-ELA

Manufacturer:	Elabscience
Preservative:	0.02% Sodium azide
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	CTRCT30,Epididymis luminal protein 113,FLJ36605,HEL113,VIM,VIME,Vimentin
Shipping Condition:	Blue Ice
Unit(s):	120 ul, 200 ul, 60 ul
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	KLH conjugated Synthetic peptide corresponding to Mouse vimentin
Application:	WB, IHC

Overview
Datasheets

Description

Description: Vimentin,also named as VIM,belongs to the intermediate filament family. Vimentin is class-III intermediate filaments found in various non-epithelial cells,especially mesenchymal cells. Vimentin is important for stabilizing the architecture of the cytoplasm. Monocyte-derived macrophages secrete vimentin into the extracellular space in vitro. Secretion of vimentin was enhanced by the proinflammatory cytokine tumor necrosis factor-alpha (TNFA; 191160) and inhibited by the antiinflammatory cytokine IL10 (124092),suggesting that vimentin is involved in the immune response. Vimentin has specialized functions that contribute to specific dynamic cellular processes. As a phosphoprotein,55-60 kDa of vimentin proteins can be observed due to the different phosphorylation level.

Additional Text

Concentration

1.1 mg/ml

Purification

Affinity Purified

UniProt ID

P08670, P20152, P31000

Antibody Clonality

Polyclonal

Store at -20°C. Avoid freeze / thaw cycles.

E-AB-70081 Protocol

Price

£167.00

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Quantity
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