IkB alpha Polyclonal Antibody
Catalogue Number: E-AB-70089-ELA
E-AB-70089 Image
E-AB-70089 Image
E-AB-70089 Image
E-AB-70089 Image
E-AB-70089 Image
Immunohistochemistry analysis of paraffin-embedded human lung cancer using IkB alpha Polyclonal Antibody at dilution of 1:500.
E-AB-70089 Image
Immunohistochemistry analysis of paraffin-embedded human stomach cancer using IkB alpha Polyclonal Antibody at dilution of 1:500.
E-AB-70089 Image
Immunohistochemistry analysis of paraffin-embedded human colon cancer using IkB alpha Polyclonal Antibody at dilution of 1:500.
E-AB-70089 Image
Immunohistochemistry analysis of paraffin-embedded Human Prostate using IkB alpha Polyclonal Antibody(Elabscience Product Detected by Lifespan).
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.02% Sodium azide |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 120 ul, 200 ul, 60 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse IKBα |
| Application: | IHC |
Description
Description: Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor,alpha (NFKBIA,synonyms: IKBA,MAD-3,NFKBI). NFKB1 or NFKB2 is bound to REL,RELA ,or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB),which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA,or IKBKB) marks them for destruction via the ubiquitination pathway,thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime.
Additional Text
Concentration
1.3 mg/ml
Purification
Affinity Purified
UniProt ID
P25963, Q9Z1E3
Antibody Clonality
Polyclonal
Gene ID
18035; 4792
Gene Name
Nfkbia, NFKBIA
Specificity
I kappa B alpha;I-kappa-B-alpha;IkappaBalpha;IkB-alpha;IKBA;IKBA;IKBalpha;MAD 3;MAD3;Major histocompatibility complex enhancer-binding protein MAD3;NF kappa B inhibitor alpha;NF-kappa-B inhibitor alpha;NFKBI;NFKBIA;Nuclear factor of kappa light chain gene enhancer in B cells;Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-70089 Protocol
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations