Recombinant E Cadherin Monoclonal Antibody
Catalogue Number: E-AB-81424-ELA
E-AB-81424 Image
E-AB-81424 Image
E-AB-81424 Image
E-AB-81424 Image
Western blot detection of E Cadherin in PC3 cell lysates using E Cadherin Rabbit mAb(1:1000 diluted).Predicted band size:98kDa.Observed band size:80-120(cleavages),130kDa.
E-AB-81424 Image
Immunohistochemistry of E Cadherin in paraffin-embedded Human Cholangiocarcinoma using E Cadherin Rabbit mAb at dilution 1:50
E-AB-81424 Image
Immunofluorescence of E Cadherin (green) in MCF-7 using E Cadherin antibody at dilution 1:20, and DAPI(blue)
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Arc 1;CADH1;Cadherin 1;cadherin 1 type 1 E-cadherin;Cadherin1;CAM 120/80;CD 324;CD324;CD324 antigen;cdh1;CDHE;E-Cad/CTF3;E-cadherin;ECAD;Epithelial cadherin;epithelial calcium dependant adhesion protein;LCAM;Liver cell adhesion molecule;UVO;Uvomorulin |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R07-4F1 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human E Cadherin |
| Application: | IF, IHC-P, WB, IHC |
Description
Description: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
Additional Text
Gene Name
CDH1
Gene ID
999
Uniprot ID
P12830
Concentration
300 ug/ml
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81424 Protocol
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