Recombinant IKB alpha Monoclonal Antibody
Catalogue Number: E-AB-81430-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | I kappa B alpha;I-kappa-B-alpha;IkappaBalpha;IkB-alpha;IKBA;IKBA;IKBalpha;MAD 3;MAD3;NF kappa B inhibitor alpha;NFKBI;IKB alpha |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R06-9E9 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human IKB alpha |
| Application: | WB |
Description
Description: Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor,alpha (NFKBIA,synonyms: IKBA,MAD-3,NFKBI). NFKB1 or NFKB2 is bound to REL,RELA ,or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB),which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA,or IKBKB) marks them for destruction via the ubiquitination pathway,thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime.
Additional Text
Gene ID
4792
Gene Name
NFKBIA
Uniprot ID
P25963
Concentration
300 ug/ml
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81430 Protocol
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations