Recombinant Bax Monoclonal Antibody

Catalogue Number: E-AB-81433-ELA

Manufacturer:	Elabscience
Shelf Life:	12 months
Preservative:	0.01% Sodium azide
Type:	Monoclonal Primary Antibody - Unconjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul, 50 ul
Host name:	Rabbit
Clone:	R03-1D3
Isotype:	IgG
Immunogen:	A synthetic peptide of human Bax
Application:	WB, IHC

Overview
Datasheets

Description

Description: BAX,also named as BCL2L4,is a pro-apoptotic member of the Bcl-2 protein family,which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells,but accumulates on the outer mitochondrial membrane upon apoptosis induction . BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane,which leads to the release of cytochrome c from mitochondria . The expression of BAX is upregulated by the tumor suppressor protein p53,and BAX has been shown to be involved in p53-mediated apoptosis .

Additional Text

Gene Name

BAX

Gene ID

581

Uniprot ID

Q07812

Concentration

300 ug/ml

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Specificity

Apoptosis regulator BAX;BAX;Bax-protein;BAX;BAXA;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;Bcl-2-like protein 4;BCL2 associated X protein;BCL2 associated X protein omega;BCL2 associated X protein transcript variant delta2;Bcl2-L-4;BCL2L4;membrane isoform alpha

Storage Note

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

E-AB-81433 Protocol

E-AB-81433 MSDS

Price

£260.00

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