Recombinant PI3 Kinase p85 alpha Monoclonal Antibody
Catalogue Number: E-AB-81435-ELA
E-AB-81435 Image
E-AB-81435 Image
E-AB-81435 Image
Western blot detection of PI3 Kinase p85 alpha in Jurkat,C6,CHO-K1 cell lysates using PI3 Kinase p85 alpha Rabbit mAb(1:1000 diluted).Predicted band size:84kDa.Observed band size:84kDa.
E-AB-81435 Image
Immunofluorescence of PI3 Kinase p85 alpha (green) in MCF-7 using PI3 Kinase p85 alpha antibody at dilution 1:20, and DAPI(blue)
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R03-3C7 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human PI 3 Kinase p85 alpha |
| Application: | IF, WB |
Description
Description: Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer,which is composed of a P110 catalytic subunit and a P85 regulatory subunit,is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.
Additional Text
Gene Name
PIK3R1
Uniprot ID
P27986
Gene ID
5295
Concentration
300 ug/ml
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Specificity
GRB1;p85 alpha;p85;P85A;Phosphatidylinositol 3 kinase associated p 85 alpha;Phosphatidylinositol 3 kinase regulatory 1;Phosphatidylinositol 3 kinase;regulatory subunit;polypeptide 1 (p85 alpha);Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;Phosphatidylinositol 3-kinase regulatory subunit alpha;Phosphoinositide 3 kinase;regulatory subunit 1 (alpha);PI3 kinase p85 subunit alpha;PI3-kinase regulatory subunit alpha;PI3-kinase subunit p85-alpha;PI3K;PI3K regulatory subunit alpha;Pik3r1;PtdIns 3 kinase p85 alpha;PtdIns-3-kinase regulatory subunit alpha;PtdIns-3-kinase regulatory subunit p85-alpha
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81435 Protocol
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