Recombinant EGFR Monoclonal Antibody

Catalogue Number: E-AB-81439-ELA

Manufacturer:	Elabscience
Shelf Life:	12 months
Preservative:	0.01% Sodium azide
Type:	Monoclonal Primary Antibody - Unconjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul, 50 ul
Host name:	Rabbit
Clone:	R03-6B1
Isotype:	IgG
Immunogen:	A synthetic peptide of human EGFR
Application:	IF, WB

Overview
Datasheets

Description

Description: EGFR,also named as ERBB1,is a cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. The gene resides on chromosome 7p12,encoding a 170 kDa membrane-associated glycoprotein. Recent studies have shown EGFR plays a critical role in cancer development and progression,including cell proliferation,apoptosis,angiogenesis,and metastatic spread. Mutations in this gene are associated with lung cancer.

Additional Text

Gene ID

1956

Gene Name

EGFR

Uniprot ID

P00533

Concentration

300 ug/ml

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Specificity

Cell growth inhibiting protein 40;Cell proliferation inducing protein 61;EGF R;EGFR;Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog);Epidermal growth factor receptor;erb-b2 receptor tyrosine kinase 1;ERBB;ERBB1;Errp;HER1;mENA; NISBD2;SA7;wa2;Wa5

Storage Note

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

E-AB-81439 Protocol

E-AB-81439 MSDS

Price

£260.00

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