Recombinant TGF beta 1 Monoclonal Antibody
Catalogue Number: E-AB-81441-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | TGF beta 1;TGFB;CED;LAP |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R08-8B7 |
| Isotype: | IgG |
| Immunogen: | Recombinant protein of mouse TGF beta 1 |
| Application: | WB |
Description
Description: TGFB, also named as LAP and TGFB1, is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for it. TGFB positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. It is highly expressed in bone. Mutation of TGFB are the cause of Camurati-Engelmann disease (CED) which known as progressive diaphyseal dysplasia 1 (DPD1).
Additional Text
Uniprot ID
P04202
Concentration
300 ug/ml
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Gene ID
21803; 7040
Gene Name
Tgfb1, TGFB1
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81441 Protocol
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