Recombinant c Myc Monoclonal Antibody
Catalogue Number: E-AB-81443-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R05-5E2 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human c-Myc |
| Application: | WB |
Description
Description: This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
Additional Text
Gene Name
MYC
Gene ID
4609
Uniprot ID
P01106
Concentration
300 ug/ml
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Specificity
AU016757;Avian myelocytomatosis viral oncogene homolog;bHLHe39;c Myc;Class E basic helix-loop-helix protein 39;MRTL;Myc;Myc protein;Myc proto oncogene protein;Myc proto-oncogene protein;myc-related translation/localization regulatory factor;MYC;Myc2;MYCC;Myelocytomatosis oncogene;Niard;Nird;Oncogene Myc;OTTHUMP00000158589;Proto-oncogene c-Myc;Protooncogene homologous to myelocytomatosis virus;RNCMYC;Transcription factor p64;Transcriptional regulator Myc-A;V-Myc avian myelocytomatosis viral oncogene homolog;v-myc myelocytomatosis viral oncogene homolog (avian)
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81443 Protocol
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