Recombinant beta Catenin Monoclonal Antibody

Catalogue Number: E-AB-81445-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Preservative:0.01% Sodium azide
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone: R06-1E2
Isotype: IgG
Immunogen: A synthetic peptide of human beta Catenin
Application: WB, IHC

Description

Description: CTNNB1,also known as β-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .

Additional Text

Gene Name

CTNNB1

Gene ID

1499

Concentration

300 ug/ml

Uniprot ID

P35222

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Specificity

Beta catenin;Beta-catenin;Cadherin associated protein;Catenin (cadherin associated protein);beta 1;88kDa;Catenin beta 1;Catenin beta-1;CATNB;CHBCAT;CTNB1;CTNNB;CTNNB1;DKFZp686D02253;FLJ25606;FLJ37923;OTTHUMP00000162082;OTTHUMP00000165222;OTTHUMP00000165223;OTTHUMP00000209288;OTTHUMP00000209289

Storage Note

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.