Recombinant ERK2 Monoclonal Antibody
Catalogue Number: E-AB-81446-ELA
E-AB-81446 Image
E-AB-81446 Image
E-AB-81446 Image
Western blot detection of ERK2 in K562,Rat Brain,C6,3T3,Hela cell lysates using ERK2 Rabbit mAb(1:1000 diluted).Predicted band size:41kDa.Observed band size:41kDa.
E-AB-81446 Image
Immunohistochemistry of ERK2 in paraffin-embedded Human Cholangiocarcinoma using ERK2 Rabbit mAb at dilution 1:20
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R07-1A9 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human ERK2 |
| Application: | IF, WB, IHC |
Description
Description: This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Additional Text
Gene Name
MAPK1
Gene ID
5594
Uniprot ID
P28482
Concentration
300 ug/ml
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Specificity
ERK 2;ERK;ERK-2;ERT1;Extracellular Signal Regulated Kinase 2;Extracellular signal-regulated kinase 2;MAP kinase 1;MAP kinase 2;MAP kinase isoform p42;MAPK 1;MAPK 2;Mapk1;MAPK2;Mitogen-activated protein kinase 1;Mitogen-activated protein kinase 2;MK01;P38;P40;P41;p42-MAPK;P42MAPK;PRKM1;PRKM2;protein kinase;mitogen-activated;1;protein kinase;mitogen-activated;2;protein tyrosine kinase ERK2
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81446 Protocol
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