Recombinant JNK Monoclonal Antibody
Catalogue Number: E-AB-81448-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R09-1G2 |
| Isotype: | IgG |
| Immunogen: | Recombinant protein of human JNK1 |
| Application: | WB |
Description
Description: MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1,PRKM8,SAPK1,SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73,mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has 4 isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa. This protein can be phosphorylated and this antibody recognizes the 46 kDa and 55 kDa bands in western blot.
Additional Text
Gene Name
MAPK8
Uniprot ID
P45983
Gene ID
5599
Concentration
300 ug/ml
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Specificity
AI849689;c Jun N terminal kinase 1;C-JUN kinase 1;c-Jun N-terminal kinase 1;EC 2.7.11.24;JNK 1;JNK;JNK-46;JNK1A2;JNK21B1/2;MAP kinase 8;MAPK 8;mapk8;Mitogen activated protein kinase 8;Mitogen-activated protein kinase 8;MK08;p54 gamma;Prkm8;Protein kinase JNK1;Protein kinase;mitogen-activated;8;SAPK 1;SAPK gamma;SAPK1;Stress-activated protein kinase 1;Stress-activated protein kinase JNK1
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81448 Protocol
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