Recombinant AKT Monoclonal Antibody

Catalogue Number: E-AB-81455-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Preservative:0.01% Sodium azide
Type:Monoclonal Primary Antibody - Unconjugated
Alias:PKB;RAC;PRKBA;PKB-ALPHA;RAC-ALPHA;AKT1 ;AKT2;AKT3
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone: R04-8A4
Isotype: IgG
Immunogen: Recombinant protein of human AKT1/2/3
Application: WB, IHC

Description

Description: Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.

Additional Text

Concentration

300 ug/ml

Purification

Affinity Purified

Uniprot ID

P31749, P31751, Q9Y243

Gene ID

10000; 207; 208

Gene Name

AKT1, AKT2, AKT3

Antibody Clonality

Monoclonal

Storage Note

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.