Recombinant FKBP52 Monoclonal Antibody

Catalogue Number: E-AB-81469-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Preservative:0.01% Sodium azide
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul, 50 ul
Host name: Rabbit
Clone: R03-4A3
Isotype: IgG
Immunogen: A synthetic peptide of human FKBP52
Application: IF, WB

Description

Description: FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.

Additional Text

Gene ID

2288

Uniprot ID

Q02790

Gene Name

FKBP4

Concentration

300 ug/ml

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Specificity

51 kDa FK506-binding protein;52 kDa FK506 binding protein;52 kDa FK506-binding protein;52 kDa FKBP;59 kDa immunophilin;FK506 binding protein 4;FK506-binding protein 4;FKBP 4;FKBP 52;FKBP 59;FKBP-4;FKBP-52;FKBP4;FKBP4;FKBP51;FKBP52 protein;FKBP59;HBI;Hsp 56;HSP binding immunophilin;HSP-binding immunophilin;Hsp56;Immunophilin FKBP52;N-terminally processed;p52;p59;p59 protein;Peptidyl prolyl cis trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidylprolyl cis trans isomerase;PPIase;PPIase FKBP4;Rotamase;T cell FK506 binding protein 59kD

Storage Note

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.