Catalogue Number: E-AB-81469-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R03-4A3 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human FKBP52 |
| Application: | IF, WB |
Description: FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs,and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics,FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's,and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function,and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition,FKBP52 is likely to play a role in growth and development of the male genitalia.
2288
Q02790
FKBP4
300 ug/ml
Affinity Purified
Monoclonal
51 kDa FK506-binding protein;52 kDa FK506 binding protein;52 kDa FK506-binding protein;52 kDa FKBP;59 kDa immunophilin;FK506 binding protein 4;FK506-binding protein 4;FKBP 4;FKBP 52;FKBP 59;FKBP-4;FKBP-52;FKBP4;FKBP4;FKBP51;FKBP52 protein;FKBP59;HBI;Hsp 56;HSP binding immunophilin;HSP-binding immunophilin;Hsp56;Immunophilin FKBP52;N-terminally processed;p52;p59;p59 protein;Peptidyl prolyl cis trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP4;Peptidylprolyl cis trans isomerase;PPIase;PPIase FKBP4;Rotamase;T cell FK506 binding protein 59kD
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.