Recombinant ILF3 Monoclonal Antibody
Catalogue Number: E-AB-81475-ELA
E-AB-81475 Image
E-AB-81475 Image
E-AB-81475 Image
E-AB-81475 Image
Western blot detection of ILF3/NF90 in Jurkat,C6,Hela cell lysates using ILF3/NF90 Rabbit mAb(1:1000 diluted).Predicted band size:95kDa.Observed band size:95kDa.
E-AB-81475 Image
Immunohistochemistry of ILF3 in paraffin-embedded Human lung cancer tissue using ILF3 Rabbit mAb at dilution 1:50
E-AB-81475 Image
Immunofluorescence of ILF3 (green) in hela using ILF3 Rabbit mAb at dilution 1:50, and DAPI(blue)
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R04-3C1 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human ILF3 |
| Application: | IF, IHC-P, WB, IHC |
Description
Description: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Additional Text
Gene ID
3609
Gene Name
ILF3
Uniprot ID
Q12906
Concentration
300 ug/ml
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Specificity
CBTF;Double stranded RNA binding protein 76;Double-stranded RNA-binding protein 76;DRBF;DRBP76;ILF3;ILF3;Interleukin enhancer binding factor 3;Interleukin enhancer-binding factor 3;M phase phosphoprotein 4;M-phase phosphoprotein 4;MPHOSPH4;MPP4;NF AT 90;NF-AT-90;NF110;NF90;NFAR;Nuclear factor associated with dsRNA;Nuclear factor of activated T cells 90 kDa;Nuclear factor of activated T-cells 90 kDa;TCP80;Translational control protein 80
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81475 Protocol
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