Recombinant Alkaline Phosphatase Monoclonal Antibody
Catalogue Number: E-AB-81527-ELA
E-AB-81527 Image
E-AB-81527 Image
E-AB-81527 Image
E-AB-81527 Image
Western blot detection of Alkaline Phosphatase in Hela,C6 cell lysates using Alkaline Phosphatase Rabbit mAb(1:500 diluted).Predicted band size:57kDa.Observed band size:80kDa.
E-AB-81527 Image
Immunohistochemistry of Alkaline Phosphatase, Tissue Non-Specific in paraffin-embedded Human lung cancer tissue using Alkaline Phosphatase, Tissue Non-Specific Rabbit mAb at dilution 1:50
E-AB-81527 Image
Immunofluorescence of Alkaline Phosphatase, Tissue Non-Specific (green) in hela using Alkaline Phosphatase, Tissue Non-Specific Rabbit mAb at dilution 1:50, and DAPI(blue)
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R08-6H0 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human Alkaline Phosphatase, Tissue Non-Specific |
| Application: | IF, IHC-P, WB, IHC |
Description
Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants have been described.
Additional Text
Gene Name
ALPL
Uniprot ID
P05186
Gene ID
249
Concentration
300 ug/ml
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Specificity
AKP2;Alkaline phosphatase liver/bone/kidney;Alkaline phosphatase liver/bone/kidney isozyme;Alkaline phosphatase tissue nonspecific isozyme;Alkaline phosphatase;tissue-nonspecific isozyme;Alkaline phosphomonoesterase;Alpl;AP TNAP;AP-TNAP;APTNAP;BAP;FLJ40094;FLJ93059;Glycerophosphatase;HOPS;Liver/bone/kidney type alkaline phosphatase;MGC161443;MGC167935;PHOA;PPBT;Tissue non specific alkaline phosphatase;Tissue nonspecific ALP;TNAP;TNSALP
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81527 Protocol
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