Recombinant MLH1 Monoclonal Antibody
Catalogue Number: E-AB-81583-ELA
E-AB-81583 Image
E-AB-81583 Image
E-AB-81583 Image
Western blot detection of MLH1 in K562,C6,3T3,Hela cell lysates using MLH1 Rabbit mAb(1:1000 diluted).Predicted band size:85kDa.Observed band size:85kDa.
E-AB-81583 Image
Immunofluorescence of MLH1(green) in Hela cells using MLH1 Rabbit mAb at dilution 1:200, and DAPI(blue)
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R02-2E8 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human MLH1 |
| Application: | IF, WB |
Description
Description: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Additional Text
Gene ID
4292
Gene Name
MLH1
Uniprot ID
P40692
Concentration
300 ug/ml
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Specificity
COCA 2;COCA2;DNA mismatch repair protein Mlh1;FCC 2;FCC2;hMLH 1;hMLH1;HNPCC 2;HNPCC;HNPCC2;MGC5172;MLH 1;MLH1;MLH1;MutL homolog 1 (E. coli);MutL homolog 1;MutL homolog 1 colon cancer nonpolyposis type 2;MutL homolog 1;colon cancer;nonpolyposis type 2 (E. coli);MutL protein homolog 1;MutL;E. coli;homolog of;1
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81583 Protocol
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