Recombinant mtTFA Monoclonal Antibody
Catalogue Number: E-AB-81584-ELA
E-AB-81584 Image
E-AB-81584 Image
E-AB-81584 Image
E-AB-81584 Image
Western blot detection of mtTFA in K562,Hela cell lysates using mtTFA Rabbit mAb(1:1000 diluted).Predicted band size:29kDa.Observed band size:24kDa.
E-AB-81584 Image
Immunohistochemistry of mtTFA in paraffin-embedded Human breast cancer tissue using mtTFA Rabbit mAb at dilution 1:100
E-AB-81584 Image
Immunofluorescence of mtTFA/TFAM(green) in Hela cells using mtTFA/TFAM Rabbit mAb at dilution 1:200, and DAPI(blue)
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R08-3E2 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human mtTFA |
| Application: | IF, IHC-P, WB, IHC |
Description
Description: This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. TFAM (Transcription Factor A, Mitochondrial) is a Protein Coding gene. Diseases associated with TFAM include Mitochondrial Dna Depletion Syndrome 15, Hepatocerebral Type and Skin Carcinoma In Situ. Among its related pathways are Mitochondrial Gene Expression and Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. GO annotations related to this gene include poly(A) RNA binding and chromatin binding.
Additional Text
Gene Name
TFAM
Uniprot ID
Q00059
Gene ID
7019
Concentration
300 ug/ml
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Specificity
anscription factor 6-like 1;Mitochondrial transcription factor 1;mitochondrial transcription factor A;MtTF1;mtTFA;TCF 6;TCF-6;TCF6;TCF6L1;TCF6L2;TCF6L3;TFAM;TFAM;Transcription factor 6;Transcription factor 6 like 2 (mitochondrial transcription factor);Transcription factor 6 like 2;Transcription factor 6-like 2;transcription factor 6-like 3;Transcription factor A;mitochondrial;Transcription factor A;mitochondrial;Transcription factor A;mitochondrial precursor
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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