Recombinant RENT1 Monoclonal Antibody
Catalogue Number: E-AB-81603-ELA
E-AB-81603 Image
E-AB-81603 Image
E-AB-81603 Image
E-AB-81603 Image
Western blot detection of RENT1 / hUPF1 in Jurkat,Hela cell lysates using RENT1 / hUPF1 Rabbit mAb(1:1000 diluted).Predicted band size:124kDa.Observed band size:124kDa.
E-AB-81603 Image
Immunohistochemistry of RENT1 in paraffin-embedded Human Cholangiocarcinoma using RENT1 Rabbit mAb at dilution 1:50
E-AB-81603 Image
Immunofluorescence of RENT1 (green) in Hela using RENT1 Rabbit mAb at dilution 1:50, and DAPI(blue)
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R02-2E6 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human RENT1 |
| Application: | IF, IHC-P, WB, IHC |
Description
Description: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.
Additional Text
Uniprot ID
Q92900
Gene ID
5976
Gene Name
UPF1
Concentration
300 ug/ml
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Specificity
ATP dependent helicase RENT1;ATP-dependent helicase RENT1;Delta helicase;FLJ43809;FLJ46894;HUPF 1;hUpf1;KIAA0221;Nonsense mRNA reducing factor 1;NORF 1;NORF1;pNORF 1;pNORF1;Regulator of nonsense transcripts 1;RENT 1;RENT1;RENT1;Smg 2;Smg 2 homolog nonsense mediated mRNA decay factor;UP Frameshift 1;Up frameshift mutation 1 homolog (S. cerevisiae);Up frameshift mutation 1 homolog;Up frameshift suppressor 1 homolog;Up-frameshift suppressor 1 homolog;UPF 1;UPF 1 regulator of nonsense transcripts homolog;upf1;UPF1 regulator of nonsense transcripts homolog;UPF1 RNA helicase and ATPase;Yeast Upf1p homolog
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81603 Protocol
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