Recombinant S100A4 Monoclonal Antibody
Catalogue Number: E-AB-81606-ELA
E-AB-81606 Image
E-AB-81606 Image
E-AB-81606 Image
E-AB-81606 Image
Western blot detection of S100A4 in Hela cell lysates using S100A4 Rabbit mAb(1:500 diluted).Predicted band size:12kDa.Observed band size:12kDa.
E-AB-81606 Image
Immunohistochemistry of S100A4 in paraffin-embedded Human lung cancer tissue using S100A4 Rabbit mAb at dilution 1:50
E-AB-81606 Image
Immunofluorescence of S1A4 (green) in hela using S1A4 Rabbit mAb at dilution 1/5, and DAPI(blue)
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R01-7H1 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human S100A4 |
| Application: | IF, IHC-P, WB, IHC |
Description
Description: S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
Additional Text
Gene ID
6275
Gene Name
S100A4
Concentration
300 ug/ml
Uniprot ID
P26447
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Specificity
18A2;42A;calcium Placental protein;Calvasculin;CAPL;Fibroblast specific protein 1 (FSP1);Fibroblast specific protein 1;Fibroblast specific protein;FSP1;Leukemia multidrug resistance associated protein;Malignant transformation suppression 1 (MTS1);Malignant transformation suppression 1;Metastasin;MTS1;OTTHUMP00000015467;OTTHUMP00000015468;P9KA;PEL98;Placental calcium-binding protein;Protein Mts1;Protein S100 A4;Protein S100-A4;S100 calcium binding protein A4 (calcium protein;calvasculin;metastasin;murine placental homolog);S100 calcium binding protein A4;S100 calcium-binding protein A4;S100a4;S10A4
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81606 Protocol
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