Recombinant Ubiquitin K63 Monoclonal Antibody
Catalogue Number: E-AB-81618-ELA
E-AB-81618 Image
E-AB-81618 Image
E-AB-81618 Image
E-AB-81618 Image
Western blot detection of Ubiquitin (linkage-specific K63) in Hela,A549 cell lysates using Ubiquitin (linkage-specific K63) Rabbit mAb(1:1000 diluted).Predicted band size:8kDa.Observed band size:8kDa.
E-AB-81618 Image
Immunohistochemistry of Ubiquitin (linkage-specific K63) in paraffin-embedded Human colon cancer tissue using Ubiquitin (linkage-specific K63) Rabbit mAb at dilution 1:50
E-AB-81618 Image
Immunofluorescence of Ubiquitin (linkage-specific K63) (green) in hela using Ubiquitin (linkage-specific K63) Rabbit mAb at dilution 1:50, and DAPI(blue)
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.01% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | UBB;UBB;Ubiquitin |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | R06-2H7 |
| Isotype: | IgG |
| Immunogen: | A synthetic peptide of human Ubiquitin (linkage-specific K63) |
| Application: | IF, IHC-P, WB, IHC |
Description
Description: This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
Additional Text
Gene Name
UBB
Gene ID
7314
Concentration
300 ug/ml
Uniprot ID
P0CG47
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-81618 Protocol
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