PIK3C2A Polyclonal Antibody
Catalogue Number: E-AB-92388-ELA
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Western blot analysis of extracts of various cell lines using PIK3C2A Polyclonal Antibody at 1:1000 dilution.
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Immunohistochemistry of paraffin-embedded mouse heart using PIK3C2A Polyclonal Antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
E-AB-92388 Image
Immunohistochemistry of paraffin-embedded rat heart using PIK3C2A Polyclonal Antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
E-AB-92388 Image
Immunohistochemistry of paraffin-embedded human liver damage using PIK3C2A Polyclonal Antibody at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
E-AB-92388 Image
Immunofluorescence analysis of C6 cells using PIK3C2A Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
E-AB-92388 Image
Immunoprecipitation analysis of 200ug extracts of HeLa cells using 3 ug PIK3C2A Polyclonal Antibody. Western blot was performed from the immunoprecipitate using PIK3C2A Polyclonal Antibody at a dilution of 1:1000.
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.02% Sodium azide |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | PIK3C2A; CPK; PI3-K-C2(ALPHA); PI3-K-C2A; PI3K-C2-alpha; PI3K-C2alpha; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha |
| Shipping Condition: | Blue Ice |
| Unit(s): | 120 ul, 200 ul, 60 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein of human PIK3C2A |
| Application: | IF, IP, WB, IHC |
Description
Description: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.
Additional Text
Gene ID
5286
Uniprot ID
O00443
Gene Name
PIK3C2A
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Concentration
1 mg/ml
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-92388 Protocol
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