DNMT1 Polyclonal Antibody
Catalogue Number: E-AB-93288-ELA
E-AB-93288 Image
E-AB-93288 Image
E-AB-93288 Image
E-AB-93288 Image
Western blot analysis of extracts of various cell lines using DNMT1 Polyclonal Antibody at 1:1000 dilution.
E-AB-93288 Image
Immunofluorescence analysis of 293T cells using DNMT1 Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
E-AB-93288 Image
Immunoprecipitation analysis of 300ug extracts of Jurkat cells using 3ug DNMT1 Polyclonal Antibody. Western blot was performed from the immunoprecipitate using DNMT1 at a dilution of 1:1000.
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.02% Sodium azide |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | DNMT1; ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI; DNA methyltransferase 1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 120 ul, 200 ul, 60 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant fusion protein of human DNMT1 |
| Application: | IF, IP, WB |
Description
Description: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
Additional Text
Gene ID
1786
Gene Name
DNMT1
Uniprot ID
P26358
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Concentration
1 mg/ml
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-93288 Protocol
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