PerCP/Cyanine5.5 Anti-Human CD86 Antibody[BU63]

Catalogue Number: E-AB-F1012J-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Alias:Activation B7-2 antigen;Cd86;ETC-1;Early T-cell costimulatory molecule 1;T-lymphocyte activation antigen CD86
Shipping Condition:Blue Ice
Unit(s): 100 tests, 20 tests, 200 tests
Host name: Mouse
Clone: BU63
Isotype: IgG1, kappa
Immunogen:
Application: FC

Description

Description: CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Additional Text

Gene Name

CD86

Gene ID

942

Uniprot ID

P42081

Concentration

5 ul/test

Antibody Clonality

Monoclonal

Storage Note

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Price
£285.00


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