FITC Anti-Human/Mouse/Rat CD47 Antibody[MIAP410]

Catalogue Number: E-AB-F1016UC-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Alias:Cd47;IAP;Integrin-associated protein;Leukocyte surface antigen CD47
Shipping Condition:Blue Ice
Unit(s): 100 ug, 25 ug
Host name: Mouse
Clone: MIAP410
Isotype: IgG1, kappa
Immunogen:
Application: FC

Description

Description: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

Additional Text

Concentration

0.5 mg/ml

UniProt ID

P97829, Q08722, Q61735

Antibody Clonality

Monoclonal

Gene ID

16423; 29364; 961

Gene Name

Cd47, CD47

Storage Note

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.