Elab Fluor® 647 Anti-Mouse CD54 Antibody[YN1/1.7.4]
Catalogue Number: E-AB-F1018M-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CD54;Icam-1;Icam1;Intercellular adhesion molecule 1;MALA-2;MyD10 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 Tests, 100 Tests, 200 Tests |
| Host name: | Rat |
| Clone: | YN1/1.7.4 |
| Isotype: | IgG2b, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues.
Additional Text
Gene Name
ICAM1
Concentration
5 ul/test
Gene ID
15894
Uniprot ID
P13597
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1018M MSDS
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