Biotin Anti-Mouse CD209b Antibody[22D1]

Catalogue Number: E-AB-F1022B-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD209;CD209 antigen-like protein B;Cd209b;DC-SIGN-related protein 1;DC-SIGNR1;OtB7
Shipping Condition:Blue Ice
Unit(s): 100 ug, 25 ug
Host name: Armenian Hamster
Clone: 22D1
Isotype: IgG
Immunogen:
Application: FC

Description

Description: CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.

Additional Text

Concentration

0.5 mg/ml

Gene ID

69165

Uniprot ID

Q8CJ91

Gene Name

Cd209b

Antibody Clonality

Monoclonal

Storage Note

This product can be stored at 2-8°C for 12 months. Do not freeze.