Elab Fluor® 488 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]

Catalogue Number: E-AB-F1028L-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Alias:B-cell surface antigen CD40;Bp50;CD40;CD40L receptor;Cd40;Tnfrsf5;Tumor necrosis factor receptor superfamily member 5
Shipping Condition:Blue Ice
Unit(s): 100 tests, 200 tests, 50 tests
Host name: Rat
Clone: FGK4.5/FGK45
Isotype: IgG2a, kappa
Immunogen:
Application: FC

Description

Description: CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

Additional Text

Gene Name

CD40

Gene ID

21939

Concentration

5 ul/test

Uniprot ID

P27512

Antibody Clonality

Monoclonal

Storage Note

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Price
£133.00


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