Elab Fluor® 647 Anti-Mouse CD40 Antibody[FGK4.5/FGK45]
Catalogue Number: E-AB-F1028M-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | B-cell surface antigen CD40;Bp50;CD40;CD40L receptor;Cd40;Tnfrsf5;Tumor necrosis factor receptor superfamily member 5 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 Tests, 100 Tests, 200 tests |
| Host name: | Rat |
| Clone: | FGK4.5/FGK45 |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Additional Text
Gene Name
CD40
Gene ID
21939
Concentration
5 ul/test
Uniprot ID
P27512
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1028M MSDS
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