PE/Cyanine5 Anti-Mouse CD122/IL-2RB Antibody[5H4]
Catalogue Number: E-AB-F1029G-ELA
E-AB-F1029G Image
E-AB-F1029G Image
E-AB-F1029G Image
C57BL/6 murine splenocytes are stained with PE/Cyanine5 Anti-Mouse CD122 Antibody and Elab Fluor® 488 Anti-Mouse CD3 Antibody (Left). Splenocytes stained with Elab Fluor® 488 Anti-Mouse CD3 Antibody (Right) are used as control.
E-AB-F1029G Image
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | IL-2R subunit beta;CD122;High affinity IL-2 receptor subunit beta;IL-2 receptor subunit beta;IL-2RB;Il2rb;Interleukin-2 receptor subunit beta;p70-75 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 Tests, 100 Tests, 200 tests |
| Host name: | Rat |
| Clone: | 5H4 |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
Additional Text
Gene Name
IL2RB
Gene ID
16185
Concentration
5 ul/test
Uniprot ID
P16297
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1029G MSDS
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