Biotin Anti-Mouse CD120b/TNFR2 Antibody[TR75-54.7]
Catalogue Number: E-AB-F1035B-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CD120b;TNF-R2;TNF-RII;TNFR-II;Tnfrsf1b;Tumor necrosis factor receptor 2;Tumor necrosis factor receptor superfamily member 1B;p75;p80 TNF-alpha receptor |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Armenian Hamster |
| Clone: | TR75-54.7 |
| Isotype: | IgG |
| Immunogen: | |
| Application: | FC |
Description
Description: CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.
Additional Text
Uniprot ID
P25119
Gene Name
TNFRSF1B
Gene ID
21938
Concentration
0.5 mg/ml
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Do not freeze.
E-AB-F1035B MSDS
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