PerCP Anti-Human CD40 Antibody[3A8]
Catalogue Number: E-AB-F1037F-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | B-cell surface antigen CD40;Bp50;CD40;CD40L receptor;Cd40;Tnfrsf5;Tumor necrosis factor receptor superfamily member 5 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 20 tests, 200 tests |
| Host name: | Mouse |
| Clone: | 3A8 |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.
Additional Text
Gene Name
CD40
Gene ID
958
Uniprot ID
P25942
Concentration
5 ul/test
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1037F MSDS
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