Biotin Anti-Human CD62L Antibody[DREG56]
Catalogue Number: E-AB-F1051B-ELA
| Manufacturer: | Elabscience |
| Preservative: | 0.05% ProClin™ 300 |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | L-selectin,Sell,CD62 antigen-like family member L,LAM-1,LECAM1,Lymph node homing receptor,Ly-22, CD62L,Lnhr,Ly22 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 ug, 100 ug |
| Host name: | Mouse |
| Clone: | DREG56 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naive lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.
Additional Text
Gene Name
SELL
Gene ID
6402
Uniprot ID
P14151
Concentration
0.5 mg/ml
Antibody Clonality
Monoclonal
Store at 2~8°C. Do not freeze.
E-AB-F1051B Protocol
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