Purified Anti-Human CD45RA Antibody[HI100]
Catalogue Number: E-AB-F1052A-ELA
| Manufacturer: | Elabscience |
| Preservative: | 0.05% ProClin™ 300 |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 25 ug, 1 mg, 25 mg, 5 mg, 50 mg |
| Host name: | Mouse |
| Clone: | HI100 |
| Isotype: | IgG2b, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/na?ve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
Additional Text
Gene Name
PTPRC
Gene ID
5788
Uniprot ID
P08575
Antibody Clonality
Monoclonal
Concentration
>=1 mg/ml
Storage Note
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
E-AB-F1052A MSDS
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