Elab Fluor®700 Anti-Human CD45RA Antibody[HI100]

Catalogue Number: E-AB-F1052M1-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD45;L-CA;Ly-5;Ptprc;Receptor-type tyrosine-protein phosphatase C;T200
Shipping Condition:Blue Ice
Unit(s): 100 tests, 2 x 100 tests, 20 tests
Host name: Mouse
Clone: HI100
Isotype: IgG2b, kappa
Immunogen:
Application: FC

Description

Description: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

Additional Text

Gene Name

PTPRC

Gene ID

5788

Uniprot ID

P08575

Antibody Clonality

Monoclonal

Storage Note

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Price
£108.00


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