PerCP/Cyanine5.5 Anti-Human CD47 Antibody[CC2C6D4]
Catalogue Number: E-AB-F1060J-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | Cd47;IAP;Integrin-associated protein;Leukocyte surface antigen CD47 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 20 tests, 200 tests |
| Host name: | Mouse |
| Clone: | CC2C6D4 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.
Additional Text
Gene Name
CD47
Gene ID
961
Concentration
5 ul/test
Uniprot ID
Q08722
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1060J MSDS
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