Elab Fluor® 488 Anti-Human CD32 Antibody[IV-3]
Catalogue Number: E-AB-F1075L-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | IGFR2;CD32;CDw32;FCG2;FCGR2B;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;IgG Fc receptor II-b;Low affinity immunoglobulin gamma Fc region receptor II-b |
| Shipping Condition: | Blue Ice |
| Unit(s): | 20 Tests, 100 Tests, 200 tests |
| Host name: | Mouse |
| Clone: | IV-3 |
| Isotype: | IgG2b, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).
Additional Text
Uniprot ID
P31994
Concentration
5 ul/test
Antibody Clonality
Monoclonal
Gene ID
2212; 2213
Gene Name
FCGR2A, FCGR2B
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1075L MSDS
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