PE/Cyanine7 Anti-Mouse CD103 Antibody[M290]
Catalogue Number: E-AB-F1090UH-ELA
E-AB-F1090UH Image
E-AB-F1090UH Image
E-AB-F1090UH Image
C57BL/6 murine splenocytes are stained with FITC Anti-Mouse CD3 Antibody and PE/Cyanine7 Anti-Mouse CD103 Antibody (Left). Splenocytes are stained with FITC Anti-Mouse CD3 Antibody and PE/Cyanine7 Rat IgG2a, κ Isotype Control (Right).
E-AB-F1090UH Image
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CD103;Integrin alpha M290;Integrin alpha-E;Itgae |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rat |
| Clone: | M290 |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium.
Additional Text
Gene Name
ITGAE
Gene ID
16407
Concentration
0.2 mg/ml
Uniprot ID
Q60677
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1090UH MSDS
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