Purified Anti-Mouse CD90.2/Thy1.2 Antibody[30H12]
Catalogue Number: E-AB-F1094A-ELA
| Manufacturer: | Elabscience |
| Preservative: | 0.05% ProClin™ 300 |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Thy-1.2 membrane glycoprotein;Thy1.2;Thy-1.2 antigen;CD90.2;Thy-1.2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 25 ug, 1 mg, 100 mg, 25 mg, 5 mg, 50 mg |
| Host name: | Rat |
| Clone: | 30H12 |
| Isotype: | IgG2b, kappa |
| Immunogen: | |
| Application: | FC, Depl, Apop |
Description
Description: CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.
Additional Text
Gene Name
THY1
Gene ID
21838
Antibody Clonality
Monoclonal
Concentration
>=1 mg/ml
Storage Note
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
E-AB-F1094A MSDS
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