Purified Anti-Human/Mouse CD44 Antibody[IM7]

Catalogue Number: E-AB-F1100A-ELA

Manufacturer:Elabscience
Preservative:0.05% ProClin™ 300
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4
Shipping Condition:Blue Ice
Unit(s): 100 ug, 25 ug, 1 mg, 100 mg, 25 mg, 5 mg, 50 mg
Host name: Rat
Clone: IM7
Isotype: IgG2b, kappa
Immunogen:
Application: FC, NT

Description

Description: CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Additional Text

UniProt ID

P15379, P16070

Antibody Clonality

Monoclonal

Gene ID

12505; 960

Gene Name

Cd44, CD44

Concentration

>=1 mg/ml

Storage Note

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Price
£69.00


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