APC Anti-Mouse CD8a Antibody[53-6.7]
Catalogue Number: E-AB-F1104E-ELA
| Manufacturer: | Elabscience |
| Preservative: | 0.05% ProClin™ 300 |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | T-cell surface glycoprotein CD8 alpha chain,CD8A,T-lymphocyte differentiation antigen T8/Leu-2,MAL |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 Tests, 200 Tests, 50 tests |
| Host name: | Rat |
| Clone: | 53-6.7 |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Additional Text
Gene Name
CD8A
Gene ID
12525
Uniprot ID
P01731
Antibody Clonality
Monoclonal
Storage Note
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
E-AB-F1104E Protocol
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