Elab Fluor®Violet 610 Anti-Human CD8a Antibody[OKT-8]
Catalogue Number: E-AB-F1110T-ELA
E-AB-F1110T Image
E-AB-F1110T Image
E-AB-F1110T Image
Staining of normal human peripheral blood cells with FITC Anti-Human CD4 Antibody[RPA-T4] and Elab Fluor® Violet 610 Anti-Human CD8a Antibody[OKT-8] (left) or Elab Fluor® Violet 610 Mouse IgG2a, κ Isotype Control (right). Cells in the lymphocytes gate were used for analysis.
E-AB-F1110T Image
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CD8A;MAL;T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 2 x 100 tests, 20 tests |
| Host name: | Mouse |
| Clone: | OKT-8 |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Additional Text
Gene ID
925
Gene Name
CD8A
Uniprot ID
P01732
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1110T MSDS
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