Elab Fluor® Red 780 Anti-Mouse CD49b/pan-NK cells Antibody[DX5]

Catalogue Number: E-AB-F1116US-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD49 antigen-like family member B;CD49b;Collagen receptor;GPIa;Integrin alpha-2;Platelet membrane glycoprotein Ia;VLA-2 subunit alpha
Shipping Condition:Blue Ice
Unit(s): 100 ug, 25 ug
Host name: Rat
Clone: DX5
Isotype: IgM, kappa
Immunogen:
Application: FC

Description

Description: DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

Additional Text

Concentration

0.5 mg/ml

Gene Name

ITGA2

Gene ID

16398

Uniprot ID

Q62469

Antibody Clonality

Monoclonal

Storage Note

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.