AF/LE Purified Anti-Mouse CD279/PD-1 Antibody[29F.1A12]
Catalogue Number: E-AB-F11310-ELA
| Manufacturer: | Elabscience |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | PD-1; Programmed Death-1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 100 mg, 100 ug, 25 mg, 25 ug, 5 mg, 50 mg |
| Host name: | Rat |
| Clone: | 29F.1A12 |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC, NT, Blk |
Description
Description: CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
Additional Text
Gene Name
PDCD1
Uniprot ID
Q02242
Gene ID
18566
Antibody Clonality
Monoclonal
Concentration
>=1 mg/ml
Storage Note
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
E-AB-F11310 MSDS
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