Elab Fluor®700 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]

Catalogue Number: E-AB-F1131M1-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Alias:Programmed Death-1;PD-1
Shipping Condition:Blue Ice
Unit(s): 100 tests, 2 x 100 tests, 50 tests
Host name: Rat
Clone: 29F.1A12
Isotype: IgG2a, kappa
Immunogen:
Application: FC

Description

Description: CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

Additional Text

Gene Name

PDCD1

Uniprot ID

Q02242

Gene ID

18566

Antibody Clonality

Monoclonal

Storage Note

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Price
£92.00


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