Elab Fluor®Violet 500 Anti-Human CD45 Antibody[HI30]

Catalogue Number: E-AB-F1137R-ELA

Manufacturer:	Elabscience
Shelf Life:	12 months
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD45;L-CA;Ly-5;Ptprc;Receptor-type tyrosine-protein phosphatase C;T200
Shipping Condition:	Blue Ice
Unit(s):	100 tests, 2 x 100 tests, 20 tests
Host name:	Mouse
Clone:	HI30
Isotype:	IgG1, kappa
Immunogen:
Application:	FC

Overview
Datasheets

Description

Description: CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

Additional Text

Gene Name

PTPRC

Gene ID

5788

Uniprot ID

P08575

Antibody Clonality

Monoclonal

Storage Note

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

E-AB-F1137R MSDS

E-AB-F1137R Datasheet

Price

£108.00

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