PE/Elab Fluor® 594 Anti-Human CD45RO Antibody[UCHL1]

Catalogue Number: E-AB-F1139P-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests, 20 tests, 200 tests
Host name: Mouse
Clone: UCHL1
Isotype: IgG2a, kappa
Immunogen:
Application: FC

Description

Description: CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

Additional Text

Gene Name

PTPRC

Gene ID

5788

Concentration

5 ul/test

Antibody Clonality

Monoclonal

Storage Note

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Price
£108.00


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