Elab Fluor®700 Anti-Human CD107a/LAMP-1 Antibody[H4A3]
Catalogue Number: E-AB-F1149M1-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | LAMP-1; LGP-120;Lysosome-Associated Membrane Protein 1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 2 x 100 tests, 20 tests |
| Host name: | Mouse |
| Clone: | H4A3 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.
Additional Text
Gene Name
LAMP1
Gene ID
3916
Uniprot ID
P11279
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1149M1 MSDS
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