PE Anti-Human CD61 Antibody[VI-PL2]
Catalogue Number: E-AB-F1166D-ELA
| Manufacturer: | Elabscience |
| Preservative: | 0.05% ProClin™ 300 |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | GP3A,GPIIIa,ITGB3,Integrin beta-3 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 20 tests, 200 tests |
| Host name: | Mouse |
| Clone: | VI-PL2 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.
Additional Text
Gene Name
ITGB3
Gene ID
3690
Uniprot ID
P05106
Antibody Clonality
Monoclonal
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
E-AB-F1166D Protocol
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