Elab Fluor®700 Anti-Mouse CD150/SLAM Antibody[TC15-12F12.2]

Catalogue Number: E-AB-F1177UM1-ELA

Manufacturer:	Elabscience
Shelf Life:	12 months
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD 150;Signaling lymphocytic activation molecule;Slam;Slamf1
Shipping Condition:	Blue Ice
Unit(s):	100 ug, 25 ug
Host name:	Rat
Clone:	TC15-12F12.2
Isotype:	IgG2a, lambda
Immunogen:
Application:	FC

Overview
Datasheets

Description

Description: CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

Additional Text

Gene Name

SLAMF1

Uniprot ID

Q9QUM4

Gene ID

27218

Antibody Clonality

Monoclonal

Storage Note

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

E-AB-F1177UM1 MSDS

E-AB-F1177UM1 Datasheet

Price

£208.00

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